Boltz2
#9 in Science & Bio AIBoltz · v2 · since Juni 2025 (Open-Source-Release angekündigt am 06.06.2025 durch MIT und Recursion) · 2× · last seen Oct 15, 2026
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Momentum
Boltz-2 is an open-source foundation model for biomolecular interactions that jointly predicts complex structures and protein-ligand binding affinity. It was developed by researchers at MIT (CSAIL and Jameel Clinic) together with Recursion and other partners and succeeds Boltz-1. Model, weights and training code are available under the MIT license; the product page is at boltz.com/boltz2.
Momentum trend
18.07.16.10.
Features
| Compliance/Certification | NVIDIA NIM container: SOC 2 Type 1 (Boltz platform per vendor page) |
| Deployment Model | Multi-tenant, single-tenant or on-premise (Boltz platform); container via NVIDIA NGC |
| Use Case Scope | Prediction of biomolecular complex structures and small-molecule binding affinity (drug discovery, virtual screening, hit-to-lead) |
| Integrations | NVIDIA NIM; partner integrations Benchling, Rowan, Tamarind Bio and others (Boltz API) |
| License | MIT license (code, weights, training pipeline) |
| Platform | Python model (GitHub code, weights); GPU-accelerated; also as NVIDIA NIM container |
| Price | Open source (free for academic and commercial use); hosted use via third parties with own pricing, e.g. Rowan with 500 starter credits |
| Release Date | June 2025 (open-source release) |